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However careful study of the observed LRC data in Figure 2 reveals 5 points in time where a peculiar change in kinetic slope is apparent, indicated with black arrows.

One example is HIV infection, where, to minimize time on treatment when side effects and resistance can develop, treatment initiation may be delayed until some immunodeficiency is apparent, indicated by low values of the biomarker, CD4 count.

The mice were sacrificed when signs of increased intracranial pressure became apparent, indicated by enlarging head circumference (a sign of hydrocephalus), head tilt, gait ataxia, or failure to eat or drink.

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His title of aetheling (an Anglo-Saxon prince, especially the heir apparent) indicates he was a prince of the royal family; he was a grandson of King Edmund II Ironside.

For both type of plots (Figs 2a,c and S2a,c green lines), a plateau-like curve was apparent, indicating that indel type error removal using fixed bases resulted in more accurate digital quantification.

The impact of the formulation on the degradation rate became apparent, indicating the shortcoming of oversimplified studies.

A dose-dependent increase in the intensity of this major band was not apparent, indicating that saturating doses of albumin must have been used here.

However, based on the estimated parameters of the linear model of the ANOVA on the proportion of 'high-memory' (goodness of fit = Radj2 = .35) a difference in distance condition depending on model complexity was apparent, indicating an ordinal interaction.

Using macroH2A2 knockout ES cells (Figure 4A), and even macroH2A2 knockout ES with knockdown of macroH2A1, the centrosomal staining was still apparent indicating that none of the three macroH2A variants is responsible for the centrosomal signal (Figure 4B).

This way, current limitations will become apparent, indicating directions for further improvements.

However, no change in Bak pI was apparent, indicating that Bak phosphorylation status does not change significantly during apoptosis.

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