Impedance of entry into the brain by the BBB may contribute to the apparent extended dormancy period of the metastatic cells present in the brain, in combination with other influencing factors.
Reported herein is also the observation that local overexpression of BAI1 disables any localized angiogenesis to such an extent that is able to induce an apparent state of dormancy in a transfected pancreatic adenocarcinoma cell line.
At present, the coat is regarded as a mechanically flexible structure capable of undergoing rapid volume expansion and contraction without any apparent effect on the dormancy of spores [6], [9].
The DosR-regulated response to hypoxia has been suggested to play a major role in mycobacterial dormancy, as is apparent from the name DosR, Dormancy survival Regulator.
Dormancy may explain the animal's apparent scarcity during cold periods.
Tumour dormancy generally describes a phase of apparent stasis in tumour growth and is mechanistically subdivided into two models.
Although sweet orange is an evergreen tree, there were no apparent developmental changes in the size or form of buds when it entered dormancy at the end of the growing season.
This concurs with the complex nature of the invasive phenotype and the apparent ability of the phenotype to revert as evidenced by phenomena such as dormancy of micrometastasis (Naumov et al, 2001) and the inefficiency of the metastatic process (Chambers et al, 2002).
This apparent inconsistency of results needs further investigation of this gene's function in seed germination and dormancy.
