However, given the small numbers of cases analyzed, any impact of treatment on survival stratified by TNP status would have had to be very large to become apparent and further larger, preferably randomized, studies are required to assess this in greater detail.
Although in-treatment 4D CBCT imaging could provide an accurate verification for clinical treatment, it is difficult to identify baseline shifts in the tumor position, which are manifested as smaller apparent breathing motion and larger apparent tumor size.
The Newton brothers and many authors after them inferred that it was flightless, due to the apparent short wings and large size shown in the 1601 Gelderland sketch.
The decreased risk was apparent both for small and large tumors and for hormone receptor positive and negative tumors (data not shown), although some of the estimates were imprecise because of small numbers of cases.
For telmisartan, additional model components for deconjugation of glucuronide metabolite and enterohepatic recirculation of the parent were added to the PBPK model to account for the long half-life and large apparent volume of distribution observed in clinical data as described before.
Species variations in co-expression patterns within the AV node are apparent between large and small mammals, possibly reflecting differences in the need for impulse delay according to heart size.
The contradiction is only apparent, as late- and large-maturing individuals were more exposed to fishing, resulting in a bias toward fish that are smaller at maturation.
RNA was isolated and microsomes prepared in thawed samples after removal of fat, fibrous tissue, and large vessels apparent in the samples.
Size and stiffness of the femoral implant are considered to be important factors regarding bone remodeling around hip arthroplasties, and negative bone remodeling is more apparent around larger and stiffer stems (Engh and Bobyn 1988, Huiskes et al. 1992, Sumner and Galante 1992, Wixson et al. 1997, Skoldenberg et al. 2006).
McCrone wrote: Even after its discovery the full significance of North Sea oil was not immediately apparent and it still remains in large measure disguised from the Scottish public by the DTI's failure to make provision for a proper Government return when the fourth round of licences was issued.
