Sentence examples for apoptosis it from inspiring English sources

Apart from its role in apoptosis, it also promotes proliferation upon weak stimulation [ 80].

In other words even if impaired double stranded break repair can lead to apoptosis it may not mean that its increased activity can prevent it.

In the absence of p53, while Pax3 no longer inhibits apoptosis, it increases proliferation in vitro and maintains its pro-tumorigenic role in vivo.

When a cell begins apoptosis, it takes a series of metabolic steps such as fragmenting its DNA or reducing its volume that eventually kills it.

Despite the unequivocal role of p53 in mediating cell-cycle arrest and apoptosis, it is still debated whether these pathways account for its widespread tumor suppressive action.

Although VE had no effect on the EPEC-related increase of enterocyte apoptosis, it clearly contributed to an acceleration of epithelial cell proliferation in the ileal crypts.

These results suggest PINC involves in the process of TNF-α induces vascular endothelial cell apoptosis, it may become a new target for KD treatment.

Underlining the relevance of this sustained JNK activation for apoptosis, it turned out to be sensitive to antioxidants.

However, in most cases of 5-aza-CdR induced apoptosis, it is generally unclear which gene or pathway leads to this effect.

Despite the detailed knowledge on individual molecule interactions underlying TNFα-induced apoptosis, it remains unclear if these interactions can explain the experimentally observed overall behavior of the system.

While blebbing is sometimes a sign of apoptosis, it has also been reported in the early phase of cell spreading [24], mitosis [34], and migration [35].