Sentence examples similar to apl trial from inspiring English sources

The rates of infection and infectious deaths have been variable on adult-predominated APL clinical trials [ 17- 19].

In trials of APL in multiple sclerosis, increased reactivity to APLs and the native myelin basic protein were noted [ 31].

With current treatment strategies, 70%to80%80 % of patients with acute promyelocytic leukemia (APL) included in multicenter trials can be cured.

This strategy was inspired by the notion that unwanted immune reactivity as seen with APLs in clinical trials is thought to occur more vividly with classic APLs modified at the TCR contact sites, which may be 'more visible' to the immune system and may thus engage and activate novel clonalities [ 30, 31].

The peptide is within the B9 23 region that is autoantigenic for CD4 T cells both in the NOD mouse and in man 16, 17 and an APL has been used in an immunotherapy trial 18.

A comprehensive literature search identified 13 randomized or quasi-randomized therapeutic trials of obstetric antiphospholipid syndrome (aPL) syndrome and all but one are appraised.

For relapsed acute promyelocytic leukemia (APL), arsenic trioxide has been tested in trials and approved by the US FDA.

This became evident in trials of altered peptide ligand (APL) therapy in MS. Treatment was terminated when it became evident that an allergic response to the peptide had been induced at the highest dose [ 46,47].

In clinical trials, the ED rate of elderly APL patients was high and ranged between 10 and 18%% (Table  4) [ 23, 31– 31].

One of the primary concerns regarding tolerogenic vaccines is the possibility that administration of a 'tolerogenic vaccine' to particular patients may be immunogenic rather tolerogenic and worsen the MS disease course, as may have occurred in clinical trials of "altered peptide ligands or APL".

The first clinical trial on arsenic trioxide treatment of relapsed APL patients after resistance to all-trans-retinoic acid (ATRA) treatment was carried out in China with a complete remission rate of 72% [ 6].