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In G2-phase, the nuclei migrate apically, entering M-phase upon reaching the apical surface.
Cappello, S. et al. The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface.
Kramer, R. H. Extracellular matrix interactions with the apical surface of vascular endothelial cells.
The significance of intense membrane trafficking at the apical surface is not known.
Human corneal and conjunctival epithelia produce a mucin-like glycoprotein for the apical surface.
Proteolytic cleavage occurs at the apical surface, and a fragment of pIgR becomes a secretory component (SC) that binds dIgA.
This notion is consistent with the role of microtubules in transporting PODXL to the apical surface in polarized ECs.
The presence of many cytoplasmic vesicles suggests that the apical surface of hair cells has a high turnover rate.
Myosin VI is required for structural integrity of the apical surface of sensory hair cells in zebrafish.
Alternatively, proteins can be sent to the basolateral surface and then endocytosed and transcytosed to the apical surface.
We developed a technique to reverse enteroid polarity such that the apical surface everts to face the media.
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