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The follicle cells often fail to move posteriorly to cover the oocyte, undergo apical constriction, and accumulate Arm apically.
Most BazS980A-expressing mutant cells underwent apical constriction to become wedge shaped, and Arm was often mislocalized apically, where it overlapped with aPKC.
Martin, A. C., Kaschube, M. & Wieschaus, E. F. Pulsed contractions of an actin-myosin network drive apical constriction.
Ji, Y.J. et al. EphrinB2 affects apical constriction in Xenopus embryos and is regulated by ADAM10 and flotillin-1.
Ji, Y. J. et al. EphrinB2 affects apical constriction in Xenopus embryos and is regulated by ADAM10 and flotillin-1.
Further, we show that disruption of Rho1 suppresses apical constriction and invagination in APC null cells.
The apical transgene also enabled the imaging of cardiomyocyte apical constriction in real time.
Furthermore, we found that Neuregulin signaling and blood flow/cardiac contractility are required for cardiomyocyte apical constriction and depolarization.
APC loss leads to segregation, apical constriction, and invagination that result from transcriptional activation of canonical Wnt signaling.
Inhibition of Notch signaling did not increase the percentage of cardiomyocytes undergoing apical constriction or of trabecular cardiomyocytes.
BACKGROUND: New branches within the embryonic chicken lung form via apical constriction, in which epithelial cells in the primary bronchus become trapezoidal in shape.
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