The selected 6 APIs from the initial cohort are not considered to be the easy cases in terms of the demonstration of bioequivalence, for instance, atorvastatin, bicalutamide, and venlafaxine.
In order to largely predict the interchangeability of currently marketed generic drugs, it was predefined to select the first six APIs from the initial cohort that had more generic drugs registered after January 1 , 2008(until June 8 , 2010.
In this study, an initial cohort of APIs was defined based on the registration date of generic drugs, which was considered to be independent of bias, for instance potential difficulties of demonstration of bioequivalence.
To avoid a selection bias, a period of January 1 to May 9, 2008 was predefined to create a cohort, which contains all APIs that had at least one generic formulation (tablets or capsules) registered during this period, regardless of the type of registration procedure.
The initial cohort contained a large number of APIs (n = 21), allowing a valid selection from the cohort.
This is the first prospective cohort study that links gut flora to API (a clinically relevant risk factor for developing asthma) at the age of 3 years.
Given limited reports on diabetes among AANHPI youth, the study examined the clinical characteristics, incidence, and prevalence of diabetes among Asian, PI, and mixed Asian-PI (API) youth in the SEARCH for Diabetes in Youth study the largest cohort of API youth with diabetes in the U.S. (40).
This retrospective cohort study further details the abuse liability of tapentadol as an active pharmaceutical ingredient (API) when immediate-release as well as extended-release formulations were on the market together (fourth quarter of 2011 to second quarter of 2016).
Entrepreneurs Roundtable Accelerator (ERA) is wrapping up its eighth cohort today with presentations from 10 startups that range from "testing as a service" provider API Fortress to personal health assistant app uGO Health.
Last year's debut TechStars London cohort included several fintech companies but our favourite, OP3Nvoice, played in the search sphere — offering APIs that make voice and video data searchable by translating its audio to text.
Last year's debut TechStars London cohort included several fintech companies but our favourite, OP3Nvoice, played in the search sphere — offering APIs that make voice and video data searchable by translating its audio to text.
