Sentence examples for apc with a from inspiring English sources

Moreover, elevated levels of VEGF associate with increased number of immature APC with a suppressive phenotype in the circulation of cancer patients.

Previously, we demonstrated that DMH-induced colon cancers, beside mutations in Ctnnb1 (coding for β-catenin) and Kras, carry single-nucleotide mutations in Apc with a frequency of about 30% [ 2].

Cellular fusions of antigen-presenting cells (APC) with tumor cells are a relatively simple and effective way to obtain highly immunogenic vaccines which combine the antigen-presenting properties of professional APC with a full repertoire of tumor antigens [ 11- 14].

Some studies demonstrated elevated levels of miR135a in colorectal tumor cells [ 20] and others identified miR135a as regulator of the tumor suppressor gene adenomatous polyposis coli (APC) with a potent effect on Wnt pathway activity.

However, the activated T cells then express the cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) molecule, which binds the B7 molecules on APC with a 10- to 20-fold greater affinity compared with CD28, and downregulates the T cell activation [ 12- 14].

In a series of 103 acetabular revisions, Böhm and Banzhaf collected 26 cases using APC, with a success rate of 83% at a mean follow-up of 4.5 years, and positive outcomes were associated with bulk allografts (88/103) protected by a support ring [ 36].

The APC monoclonal antibody (APC-NT) was raised against amino acids 1 61 of human APC with an N-terminal Flag epitope tag, produced in bacteria (Elliott, Catimel and Faux, unpublished).

At a given point, protrusion growth stops and T cell starts to pull on the model APC with an initial constant loading rate.