Sentence examples for apc through from inspiring English sources

It has also been suggested that a region of FV B domain may function in Factor VIII (a) inactivation by APC through the FV-PS-APC system [ 54- 56].

As the inhibitory effect of NBP on iNKT cell activation was alleviated by exogenous apoE, our data indicate that reduced apoE production by antigen presenting cells (APC) through NBP limits glycolipid-induced iNKT cell activation.

It has been suggested that APC through its C-terminus end (amino acids 2140-2421) interacts with DNA and negatively regulates cell cycle progression through inhibition of DNA replication by direct interaction with DNA [17].

In these adjuvant systems, the delivery vesicle serves to promote uptake and presentation of the vaccine antigen in the relevant subset of antigen-presenting cells (APC), whereas the immunomodulator activate the APC through interaction with TLR or non-TLR receptors.

Recent studies suggest that the nuclear APC, through a region (amino acids 1441-2077) that is truncated in the majority of colorectal tumors, cooperates in the recruitment of DNAPKcs to the damaged DNA chromatin and enhances early response to double-strand breaks (DSB DNAA repair [15].

The means by which Treg cells suppress tumor-specific T cells includes 1) secretion of suppressor cytokines IL-10 and TGF-β [11]; 2) suppression of the function of APC through CTLA4 pathway [12]; 3) hydrolysis of extracellular ATP to inhibitory adenosine by CD39 and CD73 [13]; and 4) transferring inhibitory cAMP from Treg cells to effector T cells through gap junction [14].

After a tense Tuesday following the Ukrainian army's recapture of an airfield outside the city, militia drove captured Ukrainian APCs through the city on Wednesday, and 14 APCs were blockaded at the nearby village of Pcholkino.

We passed rusted remains of tanks and APCs, through mounds of rubble and past flights of stairs that had no destination.

Thus, the data in the present study demonstrated that antigens coupled to oleoyl liposomes were internalized by APCs through both penetration and pinocytosis.

These findings suggest that activation of certain DC subsets and additional mechanisms triggering cytokine release by APCs through TLR activation may represent immunological correlates of protection against P. falciparum malaria.

T cell recognize donor allo-peptides presented by recipient's APCs through the indirect pathway of allorecognition [9], a mechanism that generates indirect pathway CD4 T cells and allo-Abs, both critical in the pathogenesis of CAV [10] [12] and CR [13], [14].