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"The outgoing government is not committed to handing over information of significance," one APC source said.
Consistent with our hypothesis, regression analyses suggested that the proliferation of responder T cells was significantly associated with the percentages of ERBB3+ cells of the APC source (p<0.0001, Figure 5a & 5b).
To confirm the inhibitory effect of ginger extract on antigen presentation by macrophages, we performed a primary MLR where ginger extract treated macrophages were used as the only APC source.
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13065_2013_618_MOESM1_ESM.docx Additional file 1: Text S1: LDTD-APCI Source Principles. Figure S1.
We used mitomycin C-treated splenocytes as a source of APC [27], [28], [29].
We used freshly isolated PBMC-derived adherent cells as a source of APC.
There will be other sources of APC funds, but (for example) it appears that the Wellcome Trust will only pay APCs for Wellcome-funded authors.
Mononuclear cells from the spleen of a vaccinated bird were prepared as the source of APCs.
However, the inefficient T cell activation in Bm1 BMCs suggests that translocation of peptide-MHC complexes to host APCs is unlikely the source responsible for T cell priming in B6 BMCs.
During the innate immune response monocyte-derived dendritic cells (MoDCs) which interact with the pathogen may differentiate at the inflammation site and act as local tissue resident APCs or as a source of inflammatory cytokines [ 5, 6].
Potential peptide-specific Tr clones were tested by incubation with Rh peptide (1 μg/mL) or purified Rh protein (≈ 5 μg/mL) and autologous, irradiated 30 Gy [3000 rad]), CD4+ cell depleted splenocytes at 1 × 10 cells/mL as a source of APCs for 48 to 96 hours at 37°C, 5% CO2.
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