Sentence examples for any substantial modification from inspiring English sources
DCT → PMX sequence reduced the IC50 under the level of simultaneous exposure in Capan-1 and MIA PaCa2 lines, while it did not induce any substantial modification in CFPAC-1 line.
The strengths of our study are that annual DHF incidence and case fatality ratios have been documented continuously for 45 years, using the same WHO case definition and case classification of dengue, based on both clinical and laboratory diagnostic criteria without any substantial modification throughout the surveillance period.
As seen, such changes of Na − Nd and τn lead to a substantial modification of the spectrum.
Including FLR effects leads to a substantial modification of both the instability growth rate and the instability threshold.
In addition, the proposed system is a low-cost solution because there is no need for a substantial modification of the LTE-A system architecture.
Similar to what has been obtained in the ammonia concentration variation, a substantial modification on the quasi-NRs morphology was obtained when the zinc salt concentration was altered.
Hence, in order to avoid a significant desorption of both Sb and N as well as a substantial modification of the InAs QDs, we studied the effect of the CL growth temperature in a range between 450°C and 480°C.
Our experimental observations require a substantial modification of the model of interaction between benzene molecules and graphite surfaces: in contrast to recent studies we find only weak kinetic surface friction, but a substantial dissipative interaction during inter-molecular collisions.
Addition of the bioactive phospholipid sphingosylphosphorylcholine (SPC) leads to a substantial modification of the keratin network towards a perinuclear rearrangement [8], [9].
Indeed, in comparison to our previous study, some cut-off remains quite stable (ZAP70 and microRNA-29c) while there is a substantial modification for LPL (which changes from 6 to 15) and microRNA-223 (from 82 to 138).
In summary, the presence of MyoVIIa, Atoh1, Pou4f3, Sox2, Nhlh1, Nhlh2 and Fgf8 expression in cells near intraganglionic vesicles inside the remaining ganglia implied a substantial modification of the cellular identity of these cells in Neurod1 CKO mice.
