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Moreover, in IGM the geometry is fixed at the coarsest level of discretization, and any subsequent refinement (whether h -, p - or r - ) does not change it.
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Structural modeling of nsSNPs was carried out using MODELLER [130], [131] with a subsequent refinement of side-chains by the SCRWL3 program [132].
Although path lengths swum may be initially not significantly shorter than for the scanning or chaining strategy directed search is usually the beginning of a subsequent refinement in the efficiency to reach the goal platform from each possible start position.
In a subsequent refinement of the NS1 analysis, we separated sequences for this protein into two groups, corresponding to the two major NS variants known as Alleles A and B, whose nucleotide sequences exhibit approximately 70% identity [20], [21].
That would not exclude a subsequent refinement in, for example, further mechanisms of its regulation.
This interval of letting the mean gravity stabilize for 1 h with a subsequent refinement of the slower velocity is repeated until the end of the experiment.
Thus, a higher-level supervised separation of the high dimensional feature space into the rectangular shape hyperspaces is achieved via information-theory driven decision boundaries with a subsequent refinement of decision boundaries within the identified subspaces (see Step 2).
Feedback questions concerning ambiguity, content, missing factors and format guided any necessary subsequent refinements.
Subsequent refinement was carried out at 1.4 Å using the PHENIX refine module of the PHENIX software package and manual model building in Coot [35].
Molecular dynamics based flexible fitting protocols allow subsequent refinement of the atomistic models.
"We believe that the adult-like organization of infant visual cortex provides a scaffolding that guides the subsequent refinement of responses via experience, ultimately leading to the strongly specialized regions observed in adults," Deen says.
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