The phrase "any major alterations" is correct and usable in written English.
It can be used when discussing changes or modifications that are significant in nature.
Example: "Before we finalize the design, please let me know if there are any major alterations needed."
Alternatives: "any significant changes" or "any substantial modifications."
Therefore, the reader should review co-op documents and question the current owner to determine if any major alterations have been done to the apartment.
Indeed, Watkinson believes that Moores has not made any major alterations to his style in his time away.
SSHRC program guidelines state that minor changes to a conference, such as the addition of a topic or replacement of speakers, do not require the agency's approval, whereas organizers are expected to tell the council of any major alterations in the use of the grant, such as "changing the theme or focus of the event".
Since 5'HS5 functions as a border in primitive erythroid cells, any major alterations in the 3D organization of the locus related to this property should be revealed.
We also did not find any major alterations in IFN-α family genes as a result of spironolactone treatment.
Although we did not observe any major alterations in whole muscle mass after SNT, SC depletion did lead to further declines in myofiber size and increased MCT accumulation.
The microbes in the intestine, the hypothesis holds, educate the immune cells that travel all over the body, and any major alteration in the intestine sends some wild and crazy cells out there to wreak havoc unpoliced.
Whole ISS of young individuals and prismatic layer of adults showed no evidence of any major alteration process after silver uptake.
"However, in practice, given the constant 'crisis' the airline industry always seems to be in, any major alteration to the present model is not a realistic possibility: Think the Concorde, for example".
The recovery of liver function was associated with a significant increase in serum PON1 lactonase activity, but PON1 esterase activity did not show any major alteration (Fig. 6).
We did not observe any major alteration in germination, growth and development of pap5 mutant plants compared to wild-type under optimal growth conditions (data not shown).
