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Drawings submitted after the filing date of the application may not be used (i) to overcome any insufficiency of the specification due to lack of an enabling disclosure or otherwise inadequate disclosure therein, or (ii) to supplement the original disclosure thereof for the purpose of interpretation of the scope of any claim.
Any insufficiency in this process was considered to be an error of 'not done' (a neglect of the basic requirement) and not a 'judgement error'.
Given the essential role of vitamin D in calcium absorption from the gut, any insufficiency in vitamin D negatively impacts calcium metabolism irrespective of intake of sufficient dietary or supplemental calcium [ 40, 45].
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None of their patients had any hepatic insufficiency.
The remaining patients did not experience any endocrine insufficiency (endoscopy 31%; surgery 54%).
Children with any hormone insufficiency in addition to GH or with significant chronic diseases or syndromes were excluded from the study.
Remifentanil is metabolized by unspecific blood and tissue esterases and undergoes rapid metabolism, independent of the duration of infusion or any organ insufficiency.
Therefore, a totally different approach is needed, one that involves a drug that undergoes rapid and complete metabolism, independent of the duration of infusion or any organ insufficiency.
Additionally, we did not see any sacral insufficiency fractures or sacral screw loosening or breakage, except in cases that went on to pseudarthrosis.
A different approach is to use remifentanil, which is metabolized by unspecific blood and tissue esterases and undergoes rapid metabolism, independent of the duration of infusion or any organ insufficiency.
To summarize, with long-term follow-up we found that temporary K-wire or screw stabilization of acute grade-V AC joint dislocation achieved good functional outcome, and that the sequelae were of minor importance and did not lead to any permanent insufficiency.
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CEO of Professional Science Editing for Scientists @ prosciediting.com