Suggestions(2)
Exact(3)
Sensitivity analysis for the assumed distribution of an individual potential confounder, as reported in this article, is inadequate to account for the potential effects of such a long list of known confounders and can make no allowance for any further confounding factors of which we are unaware.
Moreover, sensitivity analyses using different smoking exposure definitions (that is, defining exposure alternatively as 1) current, past, or never smoker, and 2) current or past/never smoker) did not reveal any further confounding of smoking on the main effect estimate (data not shown).
This is also in addition to any further confounding effects on the fibroblast clock that may be due to the overexpression of an artificial Bmal1 promoter construct.
Similar(57)
In the orbit, the high metabolic activity of extraocular muscles acts as a further confounding factor [69].
These effects all suggest that glucose regulation is affected by isoflurane, which is a further confounding factor in studies involving isoflurane.
A strong variability was observed in the blood glucose levels of the anaesthetised rats between scans, and from before to after the scan, which suggests that this could be a further confounding factor of isoflurane on FDG studies.
The lower SNR in estimating the fast diffusion component reduces the diagnostic value of such parameters and a further confounding factor arises from the impossibility to reach the desired low diffusion-weighting because of limitations of the scanner hardware [26].
Similarly, the patient's age, gender, level of education, and medication play a further confounding role.
Possible transient superinfections present a further confounding factor for the estimation of the prevalence of superinfection [ 2].
Furthermore, the maternal versus fetal/placental contribution to circulating angiogenic factors may be quite different, further confounding any superimposed effect of smoking.
To remove any further residual confounding by season, we included indicator variables to represent months with average monthly temperatures above 10°C (50°F) during the baseline recruitment period (all year for Los Angeles; May to October for Chicago and St. Paul; and April to October for the remaining three sites).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com