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Finally, several papers provided only partial, if any, discussion of study limitations [ 11, 16, 21, 54– 54].
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The study ends with a discussion of study endpoints, data management, and statistical analysis.
Identifying benefits of a study Researchers emphasized the importance of framing a discussion of study benefits to include personal benefits to help participants become more motivated about enrolling in a study.
In the Phase III trial (MDX010-20), HRQL outcomes were self-administered at the clinical centers before any clinical procedures or physician interactions, including any discussion of imaging studies at baseline and Week 12. Baseline to Week 12 changes in EORTC QLQ-C30 function, global health status and symptom scores were calculated.
The reader is referred to Kalfat et al. (2011) for a discussion of studies on anchorage of FRP plates.
In our discussion of study design, we are particularly interested in the essential role of randomization, and discuss recently developed randomized phase II designs.
With respect to question 10 (did the presentation and discussion of study results include all issues of concern to users), we focussed on availability, affordability, and sustainability.
All of the authors contributed to the study design, data interpretation, and discussion of study results.
The remaining authors from the Medical Practice Variations Andalusian Group contributed towards discussion of study design and revised the manuscript.
[Comment number 434] We will organise our discussion of study results in two sections.
Unbiased and frank discussion of study limitations by authors represents a crucial part of the scientific discourse and progress.
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