The phrase "any detectable impacts on" is correct and usable in written English.
It can be used when discussing the potential effects or consequences of a particular action, event, or phenomenon.
Example: "The study aimed to assess any detectable impacts on the local ecosystem following the construction of the new highway."
Alternatives: "any noticeable effects on" or "any observable consequences on".
As can be seen, neither acquisitions nor increased R&D spending had any detectable impact on the rate at which new drugs reached the market.
"China has received a lot of press coverage over the past few years for its efforts to enact greenhouse gas regulations and its efforts to become a leader on climate change, but the numbers show that China's methane regulations, in particular, have not had any detectable impact on their emissions," says Miller.
Surprisingly neither the pharmacological inhibition of the DNA damage response pathway nor silencing of p53 expression had any detectable impact on oncogene-induced senescence in human melanocytes.
Also, overexpressed p53 has significantly increased half life and proteasomal inhibitors do not exhibit any detectable impact on the levels of overexpressed p53.
This presents an enormous challenge, given that complex health interventions take time to implement and establish before they become fully operational, and show any detectable impact on mortality or morbidity figures.
There may have been some improvement in the outlook for some types of the disease in the hands of the ultraspecialist, but any such improvement can be detected only by controlled trials and is certainly too small to have made any detectable impact on the national mortality rate.
This is the first report of such a rapid and direct effect of IFNα to reduce particle specific infectivity in the absence of any detectable impact on viral RNA load, raising questions on the interpretation of early phase IFN responses that are solely based on viral RNA measurements.
EMSA assay with purified KLF4 mutant proteins showed that all point mutations at either or both residues completely abolished KLF4's binding activity to methylated motif M197 (CCmCpGCC), while none of them had any detectable impact on the binding activity to the unmethylated motif M412 (TACpGCC; Figure 3C and Figure 3 figure supplement 3).
Depletion of the MLL and SET complex component Ash2L, which is required for the conversion of H3K4me2 to the trimethylated state, was shown to cause only a mild reduction in splicing rates without any detectable impact on Pol_II recruitment and transcript levels (Sims et al, 2007).
