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Although the reinforcing properties of this stimulus are impressive at birth, the current findings do not provide any clues regarding the developmental origins of its powerful valence for the newborn and obviously call for additional investigations.
We were therefore interested in determining if the crocidolite-treated transcriptome demonstrated any clues regarding the regulation of calcium homeostasis.
It should be noticed that the BRET data indicate the aggregation status of the CX3CL1 molecule (Hermand et al., 2008) but do not provide any clues regarding the fraction of aggregated molecules or the degree of aggregation.
However, a 10-bp deletion in the 3rd LRR of BRI1 in bri1-4 introduced a premature stop in translation and did not provide any clues regarding the functional importance of the LRR domains of BRI1.
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Most of the predicted sequences exhibited the best hit against uncharacterized proteins from Phytophthora sp. and did not give any clue regarding their putative function.
However, the inspection of the chromosome neighbourhood where each ARN4 homolog resides did not provide any clue regarding the origin of this hypothetical primordial gene.
Are there any new clues regarding the identity of Deep Throat, the heralded source used by The Washington Post reporters Bob Woodward and Carl Bernstein to break open the scandal?
Analysis of TbARG using structural bioinformatics approaches has not provided any additional clues regarding a potential biological function.
Hence, while revealing that both stroke-associated SAMHD1 variant mutations were likely located in unstructured regions, which are known to be frequently involved in interactions with ligands, this information unfortunately failed to provide any direct clues regarding the possible impact of mutations on SAMHD1 structure and function.
He had known since school that uncontrolled cell division gave rise to cancer, but didn't think that his work on the molecule that produced bread and beer would yield any particularly useful clues regarding tumours.
While any statistically relevant match may offer potential clues regarding the function of a protein, matches to complexes involving ligands with high levels of cognate similarity may in addition reflect distant evolutionary relationships.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com