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To avoid confusions, we arbitrarily labelled the gene with the lowest Gene ID the sense gene and its partner gene the antisense gene.
The nanoparticle complexes with PPAA-g-PAO copolymers enhance antisense gene silencing effects in A2780 human ovarian cancer cells.
Expression of undesirable genes can be blocked by the application of antisense gene technology and RNAi technology.
Kondraganti S, Mohanam S, Chintala SK, Kin Y, Jasti SL, Nirmala C, et al. Selective suppression of matrix metalloproteinase-9 in human glioblastoma cells by antisense gene transfer impairs glioblastoma cell invasion.
In tobacco, when flavanone 3-hydroxylase (F3H) expression was suppressed by its antisense gene while soybean IFS was overexpressed at the same time, genistein yield increased prominently.
Here, we characterized transgenic tobacco plants expressing an antisense gene construct for the SUCROSE TRANSPORTER 1 (SUT1) driven by the GC specific promoter KST1.
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PCR was carried out by using Taq DNA Polymerase, recombinant (Invitrogen) in a total volume of 25 µl containing 50 ng of cDNA and 10 µM of sense and antisense gene-specific primers.
To dive into this question, we first analyzed our published PA-seq data generated from 13 human tissues and found that APA had a significant enrichment in sense-antisense gene pairs, among of which the S-AS gene pair RNASEH2C-KAT5 waselecteded to address the causality between antisense transcription and APA.
Overlapping genes involving exon regions are known as cis-encoded natural sense-antisense gene pairs [ 12, 13].
Recent studies have identified thousands of sense-antisense gene pairs across different genomes by computational mapping of cDNA sequences.
Sense-antisense gene pairs that are not directly related to cancer might also show altered expression balances in cancer tissues.
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