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Only one antisense drug, an antiviral, has made it to market.
There has been one antisense drug approved -- Isis's product to treat a viral infection that can blind people with AIDS.
One antisense drug is already on the market, and about a dozen more are in clinical trials.
They were given an antisense drug that locked onto a stretch of their RNA, near the garbled region.
Limmroth, V. et al. CD49d antisense drug ATL1102 reduces disease activity in patients with relapsing-remitting MS.
Modification of the phosphate linkage has been the first successful strategy for antisense drug developments and Fomivirsene the first antisense drug in therapy.
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After more than a decade of intense developmental work, only one antisense drug-Isis Pharmaceuticals' Vitravene, for the treatment of certain rare eye infections in AIDS patients-has won Food and Drug Administration approval.
More stable antisense drugs are now being tested in humans.
Antisense drugs act on RNA, a molecule that helps cells to make needed proteins.
Antisense drugs work essentially by shooting the messenger.
New forms of antisense drugs appear to be more potent, making them potentially cheaper and easier to administer.
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