Since carbapenem-producing organisms are often resistant to other antimicrobial classes in addition to most beta-lactams, additional susceptibility testing to antimicrobials such as colistin, fosfomycin, tigecycline, aztreonam, and rifampin is needed [ 11, 12].
Analysis limited to strains that were only R-type ACSSuT would have given a misleading result since MDR DT104 often, as mentioned, develops additional resistance to other classes of antimicrobial drugs in addition to the ACSSuT-complex.
1 Several infectious strains have acquired resistance toward most available antibiotics, which warrants global surveillance and antimicrobial stewardship in addition to increased research efforts to understand the mechanisms underlying pathogenesis and antimicrobial resistance.
Another proposed strategy to curtail the development of antimicrobial resistance, in addition to the judicious overall use of antibiotics, is to use drugs with a narrow antimicrobial spectrum.
The small-sized nanoparticles have large surface area to improve the antimicrobial activity in addition to improving chemical stability[30].
In conclusion, audits of antimicrobial use – in addition to feedback from infectious diseases specialists to individual prescribers as part of the ID consultation service – are feasible, and are needed to provide detailed and representative data about specific patterns of inappropriate prescriptions at an institution.
Patients 2 8 received β-lactam antimicrobial drugs in addition to surgical drainage of their abscesses and recovered without any complications.
IL-17 is also involved in mucosal host defense against oropharyngeal candidasis via salivary antimicrobial factors, in addition to neutrophil recruitment [ 14].
Current research has focused on Curcumin antioxidant, hepatoprotective, anti-inflammatory, anticarcinogenic, and antimicrobial properties, in addition to its use in cardiovascular disease and gastrointestinal disorders [ 14, 15].
