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In addition a different antigen (or antigenic determinant) was shown to be present in one breast carcinoma.
Affinity is a binding strength between an antigenic determinant and an antigen-binding site, and complementarity-determining regions (CDRs) account for formation of the antibody binding pocket.
The antigen-binding site is what allows the antibody to recognize a specific part of the antigen (the epitope, or antigenic determinant).
Previous studies [ 45, 46] have pointed out that antigenic determinant residues located in antigen-antibody complex tend to cluster in the space.
In other words, it involves many B cells, each of which recognizes a different antigenic determinant (epitope) of the immunizing antigen and secretes a different immunoglobulin.
The antigen receptor does not actually recognize the entire antigen; instead it binds to only a portion of the antigen's surface, an area called the antigenic determinant or epitope.
An epitope or antigenic determinant is the core part of antigen involved in the recognition with an antibody.
Untypeable strains which agglutinated with antibodies against the provisional antigen, MASF IV-1 specific for the new antigenic determinant E1037, were designated as 4X.
A comparison of these five SDSE strains, which differ in Lancefield group antigens, revealed a gene cluster presumably responsible for the synthesis of the antigenic determinant.
Pozzilli P. Beta-casein in cow's milk: a major antigenic determinant for type 1 diabetes?
Dialynas, D.P. et al. Characterization of the murine antigenic determinant, designated L3T4a, recognized by monoclonal antibody GK1.
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