"Give it up for Afghan Whigs, ladies and gentlemen!" said Usher at last year's SXSW, a sentence that nobody, not even Russell Grant could have anticipated previously.
Given that PBMC are capable of trafficking to the inner ear during inflammation [2], we anticipated that immunocytes that had previously encountered a cochlear antigen would respond differently to cochlear proteins compared with those that had not been previously exposed.
The results of this study show that the molecular epidemiology of HAV in The Netherlands can be more complicated than previously anticipated and that HAV phylogenetic studies can provide important information for the design of appropriate public health measures.
Taken together, although further experiments will be required to examine putative DNA binding cooperativity effects between ZEB1 and C/EBPβ, our data clearly demonstrate that ZEB1-C/EBPβ site co-occupancy is even more abundant than previously anticipated and that C/EBPβ may regulate ZEB1 expression, providing further support of the important regulatory relationship between ZEB1 and C/EBPβ.
These observations together with those already discussed with regard to ERSS and hardness measurements suggest that twinning may be more complicated than previously anticipated and that a more thorough investigation is called for.
This had led some analysts to expect that markdowns on some of the bank's most toxic asset classes, such as residential mortgage backed securities and collaterialized debt obligations, would be less than they had previously anticipated, signaling that the worst was over.
It has also been reported that MYCN has a much more global role in the regulation of transcription and chromatin than previously anticipated and that it is required to maintain euchromatin in a wide spread manner, including at intergenic sites [11], [57].
Furthermore, there is growing evidence that strains of the MTBC are genetically more diverse than previously anticipated and that this genetic heterogeneity indeed influences the transmissibility and virulence of clinical isolates [ 25, 26].
Gelsi-Boyer and colleagues [ 3] have demonstrated more recently that the 8p11.2-p12 amplicon is much more complex than previously anticipated and that it comprises at least four independent cores, which can be amplified independently [ 3].
We believe that our data indicate that both RNA and proteins are expressed to a more significant extent than previously anticipated and that this means that cells are regulated at the level of protein abundance rather than on mere presence/absence.
