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SAE are not anticipated in this study.
- It is useful for situations in which strong differences of opinion, e.g. due to differences in expertise and scientific backgrounds, as is anticipated in this study.
A higher dropout rate is anticipated in this study because of loss of subjects through work factors such resignation and corporate restructuring.
Future serosurveys at other sites may encounter additional local challenges not anticipated in this study, such as freezing ambient temperatures, rather than the elevated temperatures we dealt with in Ethiopia.
Considering the evidence that LWT may accentuate the contrast of bright light and placebo, we believed LWT would add to the potential light treatment effect anticipated in this study.
As anticipated, in this study the training and use of disease detector-dogs was dictated by an emergency and stimulated by environmental difficulties typical of the high mountains, hence further studies are needed to precisely identify the sensibility and specificity of such method.
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The particular challenges that we anticipate in this study are as follows: 1.
The particular challenges that we anticipate in this study are as follows: – Loss to follow-up.
This implies that there is some set of specific events that triggers the adaptive immune response of clonal expansion, but that this trigger is broader than usually anticipated in the study of T-cell responses [ 9].
This potential loss to follow-up was anticipated in the study design, with 2000 smokers recruited on the basis of a 50% dropout in order to attain adequate power.
The review process, even though not anticipated in the study protocol, was agreed with the Scientific Committee of the study.
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