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Overproduction of hedgehog ligands, gain-of-function mutations in smoothened, or loss-of-function mutations in patched (PTCH1) and suppressor of fused, all leading to constitutively activation of GLI family transcription factors are the generally anticipated cause for inappropriate hedgehog activation (reviewed in Evangelista et al, 2006).
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Metformin treatment (10 mM for 24 hours), as anticipated, caused an increase in the number of cells in G0/G1 phase relative to untreated controls.
It also anticipates causes of non-participation.
Data were not collected on days where we anticipated any exceptional cause for excitement in the tamarin colony, such as a veterinary check or lab construction.
In ecological risk assessment, RVs are concentrations in environmental compartments (soil, sediments, or water) that are not anticipated to cause adverse effects for receptors in the environmental compartments.
In ecological risk assessment, reference values are concentrations in environmental compartments (soil, sediments, or water) that are not anticipated to cause adverse effects for receptors in the environmental compartments.
Since erlotinib causes major loss of ERK activity, this would be anticipated to cause BIM stabilization.
For the initial child in the study, 44 de novo mutations were identified after birth none of which were anticipated to cause severe disease.
Global climate change is anticipated to cause some major changes in hydroclimatic conditions around the world.
Inside the news division, an announcement about cost reductions had been anticipated for weeks, causing what one employee called a "dark cloud".
But connections of Aljamaaheer, favourite for the big race on the opening day, warn that he might be withdrawn if the rain anticipated today causes the terrain to deteriorate.
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