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Then, 594 μl of CC49 monoclonal antibodies was added, resulting in a CdTe to antibody ratio of 1 4.
A chelate to antibody ratio of 3 1 was employed, using 0.1 M sodium bicarbonate buffer (pH 8.6) containing 0.9 % NaCl.
The specific activity at the time of injection was on average 45.6 GBq/μmol, which corresponds approximately a radionuclide:antibody ratio of 1 3000.
Even with optimization, conjugation to lysines results in a drug to antibody ratio (DAR) of about 2 4, with a range of 0 7 (Lazar et al., 2005; Tsuchikama and An, 2016; Beck et al., 2017).
Likewise, in the case of low-specific activity, i.e., a low nuclide to antibody ratio, of the 213Bi-mAb product, a high administered activity concentration could still lead to non-specific irradiation that could eradicate microtumors.
Adhesion of human umbilical vein ECs to polyvinyl alcohol (PVA) hydrogels was examined as a function of the relative antibody ratio (anti-VCAM1 anti-E-Selectin) anti-VCAM1 anti-E-Selectin
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Here, DR1 molecules on the B cells were labeled with "donor" fluorophore Cy3-conjugated and "acceptor" fluorophore Cy5-conjugated monoclonal antibodies at various Donor∶Acceptor (D∶A) antibody ratios.
Two dye to antibody ratios were tested for each antibody to achieve optimal sensitivity.
As previously reported (12 ), the antibody ratios of some CH1641-like samples were close to the cutoff.
The inhibition caused by antibodies was evaluated by incubation with each toxin: antibody ratios (1 : 10; 1 : 50, or 1 : 100) (w/w) for 30 min at 37°C.
Synovial fluid/serum anti-GAG antibody ratios were consistently low for IgM antibodies and were relatively high in the case of IgGs.
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