In vitro indirect MTT assay also showed that the developed drug-loaded nanofibrous scaffolds have good cytocompatibility, which was confirmed by scratch assay, indicating that the investigated scaffold may be used as antibacterial wound dressing for healing promotion.
Here, based on silk sericin, we design a series of nanoclay lithium magnesium silicate hydrate (LMSH) cross-linked semi-IPN sericin/poly NIPAm/LMSH) (HSP) nanocomposite hydrogels and demonstrate advantages in serving as antibacterial wound dressing in comparison with gauze.
Taken together, the antibacterial electroactive injectable hydrogel dressing prolonged the lifespan of dressing relying on self-healing ability and significantly promoted the in vivo wound healing process attributed to its multifunctional properties, meaning that they are excellent candidates for full-thickness skin wound healing.
Thus, some of the most relevant applications of the ENFs and ECNFs are water treatment [106], antibacterial purposes [107], wound dressing [108], drug delivery [109], sensing [110, 111] and biosensing [112], tissue engineering [113], catalyst [114], microwave absorption [115], flame retardants [116], and other biomedical issues [117, 118].
These results demonstrate that the proposed approach may be utilized in the design of antibacterial materials with promising applications in wound dressing.
NC also imparts appropriate antibacterial activity and biocompatibility promising for a wound dressing material.
The as-prepared antibacterial TPU electrospun nanofibers have potential application in wound dressing.
Thus, multifunctional composites like graphene/silver hydrogels exhibited excellent antibacterial and wound closure properties for the development a novel wound dressing.
Sericin is under investigation as a wound dressing material [19], and silk sericin-capped silver nanoparticles exhibited antibacterial activity against many gram-positive bacteria and gram-negative bacteria.
