The second scenario predicts that a shift in the agonist and antagonistic input ratio is crucial to initiate dauer formation.
The Wilcoxon Signed Ranks Test was used to test for differences between the injured and non-injured sides with respect to TSP scores, SEMGratio and for the antagonistic activity ratio within the injured side in bins 1, 6/7 and 11.
Failure to control drug ratios because of uncoordinated mechanisms or pharmacokinetics could therefore lead to drug resistance if the tumor cells are exposed to antagonistic drug ratios.
LSG combined with CBZ or PHT showed additivity, whereas the combinations of LSG with PB were either additive, for the fixed ratios of 1 3 and 1 1, or antagonistic for the ratio of 3 1 (ED50add = 18.4 mg/kg versus ED50mix = 26.7 mg/kg, p < 0.05).
To quantitatively characterize the activity in antagonistic muscles, a ratio of SEMG activity of quadriceps/hamstrings and tibialis anterior/gastrocnemius was calculated for bin 1, 6/7 and 11.
The RMS ratio of antagonistic to agonist muscle activity increased with the increase of velocity, suggesting that antagonist exhibited relatively higher activation at higher velocity.
This study shows that alterations in the expression of IAP family members, as well as a marked imbalance of the expression ratio of antagonistic regulators, such as XIAP/XAF1, play an important role in HCC and patient's prognosis.
Herbart next considers the proportion in which the inhibition sum is spread out over the various, mutually antagonistic representations; this proportion is what he calls the "inhibition-ratio" (SW V: 285, ff. [§43]).
There was a dose-additive interaction for the inhibition of brain ChE for the 2 1 ratio, but an antagonistic effect for the 1 1 ratio.
In a sample of siblings, we identified and measured sexually dimorphic traits and hormones within each sex that are related to fitness and are likely coded for by antagonistic genes: waist-to-hip ratio (WHR) and breast size in women, WHR and bicep size (an index of muscularity) in men, and estradiol (E) and testosterone (T) in both sexes.
Recent observations indicate a tight regulation of all components and suggest that the relative expression ratio of these antagonistic regulators, rather than the expression of a single factor, determines susceptibility for apoptosis.
