Sentence examples for antagonism activity from inspiring English sources
No indifference and antagonism activity was observed for any of the combinations designed.
Three Trichoderma species, i.e., T. viride (FCBP 644), T. harzianum (FCBP 1277), and T. hamatum (FCBP 907), were tested for their antagonism activity against M. phaseolina (FCBP 0751).
Of those studied, the most highly selective variant was con-T[M8I], which showed maximal NMDAR ion channel antagonism activity toward the NR1a/2A subtype.
The best antagonism activity in this series was exemplified by compound 13a, which combined the optimal substitutions of 3,4-dichlorophenylamino at C-1 and 3- 4- N-methylmethylsulfonamido)piperidin-1-yl)propyl at N-6 position, leading to an IC50 value of 61 nM and 10-fold selectivity for CCR2 over CCR5.
This new structure explains the RXR full antagonism activity of LG100754.
VER was discovered first but was limited in application as a P-gp inhibitor, as its calcium antagonism activity led to cardiac toxicity.
As with HCoV-NL63 PLP2-TM, the PLpro-TM of SARS-CoV, MERS-CoV PLpro-TM and PLP2-TM of PEDV also possess de-ubiquitinating and interferon antagonism activities (Clementz et al., 2010; Devaraj et al., 2007; Xing et al., 2013; Yang et al., 2014).
This drug combines selective postsynaptic α1-adrenergic antagonist activity with central antagonism of serotonin receptors, which gives it a potent vasodilatory effect reducing both pre- and afterload, as well as causing pulmonary and renal vasodilation, without any significant effect on cardiac function.
The significance of the lack of effect of CB2 receptor antagonism on spontaneous activity compared to burst activity is poorly understood, but it suggests that CB2 receptors play a role in tonic inhibition of neuronal activity in the VPL.
Various β-blockers are available, with different degrees of specificity for β1-receptor antagonism, intrinsic sympathomimetic activity, membrane-stabilizing properties, capacity to induce vasodilation, lipid solubility, half-life, onset of action, and routes of administration [57].
Antagonism of BMP activity by noggin is critical for embryonic chondro-osteogenesis and joint formation [40].
