Sentence examples for anp through from inspiring English sources

The reduced excretion of cGMP in nephrotic rats, despite elevated plasma ANP levels, provides a means to link the blunted volume expansion natriuresis to the previously demonstrated resistance to infused ANP through a cellular defect in the accumulation of its intracellular second messenger cGMP in target tissues [ 6, 7].

Their expression levels detected by immunostaining were in line with the results from RT-PCR and western blotting, indicating that TLR4 played an important role in LPS-induced ANP through mediating the levels of Traf6 expression.

Based however on the direct p600/Ndel1 interaction, the dominant-negative effect of the Ndel1-binding p6004480 5183, and the close phenotypic similarity between p600 conditional null, Ndel1 and Lis1 knockout mice, we propose that p600 controls spindle orientation of mitotic aNPs through the well-characterized actions of the Ndel1/Lis1/Dynein complex.

The promising effects of NO inhalation in ARDS [ 9, 10] also supported this hypothesis, because both NO and ANP act through activation of guanylate cyclase.

Taken together, these findings suggest that the decrease of ICaL by ANP is mediated through an increase of cGMP levels, thereafter activation of cGMP-stimulated PDE2, enhancement of cAMP breakdown, decrease of PKA levels, and ultimately reduced phosphorylation of voltage dependent Ca2+ channels (VDCC) or a closely associated protein.

Moreover, the addition of hydrocortisone (an extraneuronal dopamine transporter inhibitor) reversed ANP-dopamine overinhibition of the enzyme, demonstrating that ANP enhances dopamine uptake through tubular transporters [ 17].

ANP and BNP act through the same membrane-bound guanylyl cyclase receptor GC-A or NPR1 (gene name in mouse: Npr1), while CNP acts through GC-B/NPR2 (Npr2) to initiate the cGMP-signaling cascade [ 9].

ANP and dopamine systems, through their second messengers and associated protein kinases or protein phosphatases, initiate a cascade of events ultimately resulting in the phosphorylation and inhibition of the enzymatic activity of Na+, K+-ATPase [ 2, 17, 43].

When the priorities vary across the time, AHP and ANP need to be dynamic through the use of numbers or functions and then derive either numbers that represent functions like expected values, or derive functions directly to represent priorities.

Some genotypes from Ankara/Ayaş (pop AA) migrated through Ankara/Polatlı (population ANP) and Eskişehir (population E) (Figure 2).

ANP is known to act through direct stimulation of the particulate guanylyl cyclase/cGMP- as well as through a G protein mediated inhibition of the adenylyl cyclase/cAMP system [9] [11].