Still, the only serious drawback of the concerts was the placement of the orchestra at the edge of the stage.
A serious drawback of the flux estimation method in current use is that it does not produce confidence limits for the estimated fluxes.
A serious drawback of guide based approach is that it necessitates repeated analysis of the entire structure within the GA iterations.
Unfortunately, a serious drawback of the inspection experiment is that the results may be influenced by an unknown time trend because of inspector fatigue due to monotony of the inspection task.
A simple method for the filter design is presented which is aimed at overcoming the most serious drawback of advanced filtering algorithms for high dimensional systems related to very high computational cost in evaluation of the filter gain.
Up to now, of course, the most serious drawback of the whole Left Wing philosophy has been its lack of the lighthearted carnality of capitalistic enterprises, typified for us by the bosomy girls we see at Republican rallies or leading American Legion bands.
A serious drawback of thermoelectrics is poor efficiency [28].
And that has been considered a rather serious drawback of patent pools.
Similarly ifosfamide causes encephalopathy (brain dysfunction), a very serious drawback of the drug.
One serious drawback of the solution approach is the bundling of individual CNTs.
