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No associated abnormalities were reported in the cases with RET mutations, although mutations in this gene have been associated with another malformation, Hirschprung disease (OMIM 142623) [42].
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This appears to be so for Q62.0 (congenital hydronephrosis) and Q63.0 (another malformations of kidney, unspecified), as they represent more than a half of all urinary malformations in Monchegorsk.
About 9.6% of individuals in the Danish Facial Cleft Database have another major malformation besides oral clefts or a genetic syndrome [ 38].
Another disorder of notochord malformation is segmental spinal dysgenesis [50], which includes agenesis or dysgenesis of the thoracic or lumbar spine, alterations of the spinal cord and nerve roots, congenital paraparesis or paraplegia, and deformities in the lower limbs.
Another calf had Arnold-Chiari massociatedn associated with lumbar spina bifida and bilateral posterior arthrogryposis, while an other had tetralogy of Fallot and bilateral abdominal cryptorchidism.
Therefore, due to the exposure of TBT, the lower level of Vg and Vt content during ovarian maturation was noticed as an indication of malformation at another point of the reproductive endocrine system.
Another had signs of bone malformation.
This is consistent with another study that reported congenital malformation as one of the causes of death in developing countries [ 7].
Another study demonstrated morphological evidence of vascular malformation using angiograms.
Another characteristic symptom is a distinct craniofacial malformation complex, consisting of high forehead, low/broad nasal bridge, epicanthus, high arched palate, and micrognathia.
Another phenotype of the mutant mice includes eye malformation (Xuan et al., 1995; Pratt et al., 2004).
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