Another major weakness was lack of further assessment of viral DNA presence or immunohistochemistry findings in cancer tissue samples.
Another major weakness is that none of the included studies followed patients to assess progress, all studies involved single visits.
Another major weakness stems from the use of Framingham risk score in HIV-infected patients.
According to an editorial by Kathleen Basile, another CDC researcher, which accompanied the NEJM article, the major weakness of Senn's study "is that it places the onus for prevention on potential victims, possibly obscuring the responsibility of perpetrators and others.
Herein lies a major weakness of the powerful: they easily assume that the weak will give up in the face of overwhelming force.
Crack formation and progression under tensile stress is a major weakness of concrete.
Mr. Gore's style had seemed a major weakness of his candidacy.
A major weakness of the Manchester plan could turn out to be the complicated governance arrangements.
The third and major weakness of the case appears to be the star witness.
A major weakness of Bradford's work is his reliance on stereotypes of his black subjects.
