All RCTs sponsored by sanofi-aventis that compared the use of insulin glargine with another active comparator in either type 1 or type 2 diabetes and had a treatment duration of at least 4 weeks were included in this analysis.
The fertility bust Reprints Related items Russia's new DumaDec 23rd 1999Mussolini was once another fashionable comparator.
However, in factorial trials of lithium, placebo, and another active comparator, we included both the lithium versus placebo and the lithium versus active comparator comparison because the factorial design allows an unconfounded comparison.
We sought trials comparing the effect of a DA with either placebo, standard treatment or another active comparator.
It remains to be specified whether the clinical trials required for an abbreviated BLA may demonstrate non-inferiority of the biosimilar to the reference product or must prove superiority of the biosimilar to placebo or to another active comparator.
However, five of these studies did not report statistically significant differences between dietary arms in the reductions in HbA1c values, and hence do not appear to support the use of one dietary intervention over another, as comparators had similar positive effects on glycaemic control.
Another bench mark comparator is the EU RED [106], which requires biodiesel to be produced with a GHG emission of less than 42 g CO2eq MJ−1.
The reviewers considered these suitable for inclusion if they reported on randomized trials, compared β blockers versus another β blocker or comparator in patients with heart failure with reduced ejection fraction, and reported mortality.
