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Such methods study over-representations of functional annotations in groups of differentially expressed genes [ 3- 8].
Moreover, the DrugMatrix Toolbox provides tools to mine the literature and to identify enriched literature annotations in groups of expression profiles.
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The differential distribution of certain GO annotations in the group of cancer genes delineates trends in the functions and biological processes of the genes whose altered function or expression results in oncogenesis.
Restricting visibility of annotations to groups of users, as usually enforced in enterprise collaboration systems, turns annotations into a tool for focused collaboration among users with common interests.
The Functional Annotation Clustering algorithm was used to generate a report of related annotation terms and groups of annotation clusters.
For example, are results scored by document, individual annotation or by groups of related annotations?
This software allows the evaluation of differences in annotation between two groups of data.
Annotations in this group fall into two categories.
The annotations in the Cluster of Orthologous Groups (COGs) of Proteins system are classified into functional categories that allow for inferences on biological processes.
Here, each network is weighted according to its usefulness in predicting annotations for a group of genes that share a known specific function.
Analysis of these ontology annotations in the four groups showed an interesting pattern.
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