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We mapped all new annotations back to the GeneChip® sequences through BLAST analysis.
The database runs in parallel to the central archive, and incorporates user comments in a semi-structured way, allowing for the possibility of incorporating annotations back into the PDB.
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Thus, document collections, users, configurations, annotations, back-end data storage, as well as the tools for document processing and TM, are all managed centrally.
Electronic annotations are slowly being replaced with higher-quality annotations backed by experimental evidence; however, given the slow pace of experimental validation and manual curation, the preponderance of unreviewed computational annotations and continual generation of new automated annotations, annotation quality will remain a challenge into the foreseeable future.
Users save annotation back to the master Otter annotation databases.
We also mapped the RNA-Seq data used for annotation back to the genome to assess transcriptome coverage.
As functional assignments are made, Manatee stores not only the updated annotation data, but also the underlying evidence used to make that annotation, back into the database.
Intertool communication (such as annotation and back annotation) between Capture and PCB Editor is also demonstrated.
This service also provides streaming of alignment and annotation results back to the appropriate BRC so that users can view results in the relevant BRC, using annotations and tools provided in support of transcriptomic analysis.
But Web annotation is back with the launch today of Google's Sidewiki.
To date, GEP students under the guidance of their faculty advisors have submitted 168 annotation projects back to the GEP.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com