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The annotation focused on the specialised, detailed results, which provide novel information and extend the currently available annotations data for salmonidae.
In order to identify pronounced, age-related changes in gene expression in the ovary, we conducted further functional annotation focused on GOTERM_BP_FAT and KEGG_PARTHWAY of 51 orthologs genes upregulated in old versus young ovary and 58 orthologs genes downregulated in old versus young and middle-aged ovary in old ovary (Table S4).
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For example, TAIR annotation focuses on re-annotation and curation of an annotated genome.
In the next section we present the state of the art approaches for video annotation focusing on collaborative and content analysis methodologies.
Most proteome-wide functional annotation focuses on sequence similarity, however, this ignores valuable information that protein structure can provide an important consideration in the era of structural genomics when many more protein structures are becoming available [1].
This group is responsible for the Institute's; large-scale manual annotation, focusing on the reference genomes of human, mouse and zebrafish, and is also involved in smaller collaborative projects such as the annotation of the MHC region in different human haplotypes and other mammals (e.g. dog, wallaby, gorilla).
Our annotations focused on the 'nine-spined stickleback transcriptome' that was assembled with all reads combined from the four cDNA libraries.
Previous rounds of annotation focused primarily on protein-coding genes.
Currently, our literature annotation is focused on providing Gene Ontology (GO) annotation for agricultural gene products from chicken, cow, corn and cotton and Plant Ontology (PO) (2) annotation for cotton.
The Cardiovascular GO Annotation Initiative is currently the only GO annotation project focused on a specific field of human biology.
Because of its rich annotation, we focused on S.cere., using the automatically defined ortholog set.
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