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In the area of prokaryotic genome annotation, existing NGS-related studies have focussed on the possibly increased level of sequencing errors associated with such technologies.
Using the information of cellular component annotation existing in GO, Liu et al. [ 31] define a localization group as the set of proteins annotated with a common informative cellular component GO annotation.
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Huge quantity of images and their annotations, existing in MARVEL, makes it applicable to directly employ recent methods utilizing deep architectures such as AlexNet [2] for vessel categorization.
In addition to continually generating new annotations, existing annotations must also be reviewed and updated regularly.
RE ANNOTATE creates up to three new 'layers' of repetitive DNA annotation over existing R EPEATM ASKER[ 20] annotation taken as input.
Although results from these methods clearly demonstrate the added-value of genomic context analysis in the process of prokaryotic genome annotation, only few existing annotation systems systematically integrate them.
Inconsistent and incomplete (and sometimes outdated and inappropriate) annotation of existing ad hoc reference sequences and missing annotation of clinically relevant transcripts is an additional problem.
Using the RNA-Seq transcriptome sequences from 25 diverse tissue types, the re-annotation pipeline improved existing annotations by increasing the annotation accuracy based on extensive transcriptome data.
Biocurators have the option of selecting either to discard duplicated annotations from the upload file or to use these annotations to override existing annotations in the BI with the newer annotations.
We have analyzed each of these genes from these categories and have improved the annotation of existing gene models in L. donovani.
The annotation of existing DUFs seldom keeps pace with new DUFs being added.
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CEO of Professional Science Editing for Scientists @ prosciediting.com