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The REGs' annotation describing their possible roles (Table 4) will be incorporated into the ppdb in the near future.
These included specimen-level annotation describing the overall case where a bio-specimen was collected, block-level annotation which records information on individual pieces or sections of the bio-specimen banked, and follow-up information about treatment, vital status, and clinical recurrence.
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Later, the annotators assessed pre-computed gene families for consistent gene structures concurrent with functional annotation (described below).
GO annotation describes the similarities between genes within one network, which facilitates further characterization of the relationships between genes.
In the top 30 over- and under-expressed genes in AD between the 3 brain samples, there are a number of genes without annotation, described either as putative or novel transcripts in the Ensembl database.
The original annotation described 787 genes encoding hypothetical proteins.
In the bovine species, genomic annotation describes two MAGI2 genes in close neighborhood.
Distances from these bins to ncRNA genes were measured using the SGD genome annotation described above and BEDTools [ 52].
In order to identify processes where gene expressional changes occur, a gene ontology (GO) enrichment analysis was done based on the extended functional annotation described above.
The manual curation led to the final annotation described in Table 3 and is available on the browser https://iant.toulouse.inra.fr/S.meliloti2011.inra.fr/S.meliloti2011
This annotation describes some early rat studies which conclude that parathyroid hormone (PTH) has more dramatic stimulatory effects on bone repair than on untraumatized bone.
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