However, review of the Ensembl annotation utilized for the analysis in this study revealed only 20 genes annotated to be on the Y chromosome.
Additionally, 40 unigenes were annotated to be involved in the biosynthetic steps from GGPP to taxol within 'diterpenoid biosynthesis' pathway.
One potential and partial taxol biosynthesis pathway in C. cladosporioides MD2 was speculated, and dozens of unigenes were annotated to be involved in taxol biosynthesis.
A PCA (Figure 2) was performed for the compounds annotated to be active against plasmodial DHFR and those active against T. gondii DHFR.
Based on the KEGG analysis, 40 unigenes in the C. cladosporioides MD2 transcriptome were annotated to be related to the fungal taxol biosynthesis, and were homologous to the genes for TS, T5αH, T13αH, and TBT, respectively.
All of these seven proteins are annotated to be bound by MSH2, RFC4 and MSH6.
In the S. gregaria database several ESTs were annotated to be involved in GPCR signaling pathways (GO: 0007186).
Genes annotated to be attached to the membrane by a GPI anchor were manually extracted from databases and added to the list.
This control dataset was constructed to check the trend for all human proteins from the SwissProt database that are not annotated to be involved in any disease.
The Gene Ontology (GO) analysis revealed that AtWAKL10 is annotated to be part of the endomembrane system, have kinase activity and function in protein amino acid phosphorylation.
Consistently, surface proteins annotated to be 'signal transducers' are significantly enriched in both hES cells and hSperm (By Molecule Function enrichment study by DAVID, Data not shown).
