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melD is found on the linear chromosomes of four Streptomyces species that have been sequenced and annotated so far.
However, this gene was poorly annotated so far.
More than 2,500 mature human miRNA sequences have been annotated so far (http://www.mirbase.org) [ 3].
Interestingly, about 50% of the genes with anther-specific expression have not been annotated so far.
Hence, not all families of factors annotated so far in eukaryotes were found in the parasite.
The slight decrease in specificity probably implies the discovery of previously unknown epitopes in the tertiary structures, as the epitopes have not been fully annotated so far.
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These " dark matter RNAs", which have remained largely un-annotated so far, can in fact be the dominating non-ribosomal RNA component in a mammalian cell [ 6, 7].
Especially for E. coli, who has the largest number of completely sequenced and annotated genomes so far, we find that the pan-genome is significantly larger than the human genome.
LOC488837, is so far annotated as a model protein.
151 are so far annotated only in pig, however, only 5 appear to be confined to the Laurasiatheria, 4 found only in pig and one specific to the cow/pig/dolphin part of the tree.
The 149 NBS-LRR-encoding genes and the 58 related genes that do not encode LRRs represent approximately 0.8% of all ORFs so far annotated in Arabidopsis ecotype Col-0.
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