Books are annotated with reviews by around 40% of users and rated by 75%.
In addition, all annotated and reviewed P. falciparum targets from Uniprot were downloaded, resulting in a total of 148 P. falciparum protein targets.
All the assembled unigenes were searched against the following 7 database, including Nr (NCBI non-redundant protein sequences), Nt (NCBI non-redundant nucleotide sequences), Pfam (Protein family), KOG/COG (Clusters of Orthologous Groups of proteins), Swiss-Prot (A manually annotated and reviewed protein sequence database), KO (KEGG Ortholog database) and GO (Gene Ontology).
The databases used for gene annotation in this study included: nr (NCBI non-redundant protein sequences), nt (NCBI nucleotide sequences), Pfam (Protein family), KOG/COG (euKaryotic Ortholog Groups/Clusters of Orthologous Groups of proteins), Swiss-Prot (a manually annotated and reviewed protein sequence database), KEGG (Kyoto Encyclopedia of Genes and Genomes) an GO (Gene Ontology).
97,339 (94%) articles were annotated as reviews, editorials or letters rather than primary research, and were excluded.
To ensure the reliability of data, we only selected manually annotated and reviewed proteins.
In UniProt, a query was constructed to search for all manually annotated and reviewed human GPCRs.
The curated database provides information that was manually annotated and reviewed, even if it was obtained electronically.
Sequences are also listed depending on the UniProtKB branch from where they were retrieved (SwissProt, manually annotated and reviewed, and TrEMBL, automatically annotated).
