The results were compared to PROSITE annotated patterns and three other pattern mining methods: RISOTTO, Teiresias, and Pratt.
In addition, the annotations can be assembled into a database, so we can apply algorithms that automatically recognize previously annotated patterns.
The project had precedent in Joe Clark's PR-Otaku, an attempt at logging and annotating Pattern Recognition, but whereas that took several years to develop, Node was complete before the novel was even published.
Here, we call the pattern to be annotated as main pattern, and its similar patterns can be found by using the Word2Vec model.
In summary, we show that the developed workflow is capable of describing the different manually annotated localization patterns in real experiments.
We found that C2C12 cells with three different manually annotated localization patterns (DYNC1H1 - foci, KIF1C - cellular extension, ACTN1 - random and polarized) were well separated.
Each data point links to the chemical structure of each molecule and the images associated with each molecule including Hoechst, FITC, TRITC and Cy5 channels, the predicted localization and annotated staining patterns.
The dataset of positive embryos is reported comprehensively in terms of sequence coordinates, flanking genes, annotated expression patterns and details of reproducibility of each structure, images of individual embryos, and series of histological sections [ 17].
A DNA microarray analysis is an appropriate method not only of annotating the pattern of expression of our full-length cDNAs, but of demonstrating that our strategy for finding novel gene works well.
Normally, most of similar patterns have the same annotation tag as the main pattern, so one click or keystroke can annotate many patterns (see Fig. 2).
