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Although this is a valid extended model, the animals were small compared to humans (average of 25 kg), and the use of other clinically relevant interventions, such as vasopressors, inotropes and hormone resuscitation, were not reported.
However, the differences in the ranking of animals were small, i.e. a 1 to 5% difference in accuracy.
Aside from the heart rate, overall differences of physiological variables between the two anesthetic groups of animals were small, and the animals had uneventful recoveries from the anesthesia.
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There were four plowshares in the bin, but the two new animals were smaller.
The ER animals were smaller but had developed bone strength sufficient for their size.
Calluses from macrophage-deficient animals were smaller, and contained less bone and more fibrotic tissue deposition.
As a result, the eyes of injected animals were smaller and also exhibited strong lamination defects [28].
However, the animals were smaller compared to wild type mice.
The resultant tumours excised from the soy-fed animals were smaller in size and exhibited a more differentiated phenotype compared with control animals [ 42].
Importantly, TGMAT mice surviving to P6 were indistinguishable from WT littermates, but at P21 mutant animals were smaller and appeared developmentally delayed.
Macroscopic observation showed that ovaries from the BPA-exposed animals were smaller than those from controls, as confirmed by ovarian weight; there were no differences in body weight.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com