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Improvement was accelerated in animals receiving either NSC-Ad or Ad-HIF-1α, while improvement at all times between 7 days and 28 days post MCAO was significantly greater in animals transplanted with NSC-Ad-HIF-1α than for other treated animals.
Latency to tumor onset was prolonged in animals receiving either of the combination treatments compared with controls, and tumor multiplicity was also significantly decreased.
Coronal sections of the spinal cord taken from animals receiving either moderate or severe displacement injuries are shown in Figure 2b.
The histological absence of significant differences in the multiple parameters of host response after hCNS-SCns transplantation was supplemented with biochemical analyses to determine protein expression levels in spinal cord-injured animals receiving either hCNS-SCns or vehicle at 9dpi.
Only few studies transplanting NSCs into the injured spinal cord of immunosufficient animals receiving either cyclosporine or tacrolimus have attempted to numerically quantify total cell numbers at the time of sacrifice and report poor cell survival, ranging from 0.1% 37% [3], [5], [79], [80].
There was no effect in animals receiving either drug alone or light alone.
Similar(41)
The pattern of infusions for each triad was determined by the animal self-administering nicotine; the other two animals received either yoked nicotine or saline.
Immunosuppressed animals received either lumbar RN46A-B14 (n = 24) or control RN46A-V1 (n = 24) empty-vector transplants or no cell (n = 24) transplant.
After 10 min of VF, animals received either immediate defibrillation (followed by treatment with bicarbonate or control) or immediate treatment with bicarbonate or saline (followed by defibrillation).
Animals received either a good quality hay or a medium quality hay (three cows per breed for each hay, according to Latin square designs).
Following a 120-minute basal sampling period, sham and infected animals received either intraportal saline or N[omega ]-nitro-L-arginine (L-NNA; 37 [mu ]g [middot] kg[minus ]1 [middot] min[minus ]1) infusion for 180 minutes.
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