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Knockout animal analyses revealed that autotaxin controls the levels of LPA in the blood circulation [8], [9].
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While the ACORN assessment (Nehm and Ha 2011; Opfer et al. 2012) contrasted items with plants and animals, analyses of student responses to those items quantified the frequency of intuitive responses rather than identifying differences in types of intuitive responses for plant versus animal items.
As human behaviours are often not faithfully modelled in animal systems (Nestler and Hyman, 2010; O'Leary and Cryan, 2013), whole-animal analyses might be most useful when they focus on specific molecular and cellular pathways that underlie a pathology.
The number of experiments and animals analysed are indicated in each figure.
Data and graphs are presented as mean ± SEM, and 'n' values refer to the number of cells, cultures, tissue samples or animals analysed per group.
In this case, four out of five ECTVIFNα/βBPGAGmut -infected animals analysed exhibited higher protection levels against IFN than the mean value from WT ECTV infections.
In brief, the animals analysed here were severe combined immunodeficiency (SCID) mice carrying subcutaneous tumour xenografts of head and neck (FaDu) and epidermal (A431) and ovarian (SKOV-3) carcinoma cell lines.
However, the difference in the level observed in the liver, kidney and cardiac enzymes of the two treated groups were not significantly different to that of control animals analysed by one-way ANOVA (P > 0.05).
The same chimeric animals analysed for blood-based trogocytosis in the previous section were further analysed for non-blood tissue based trogocytosis.
The number of animals analysed is indicated for each genotype.
AC provided samples, phenotyped animals, analysed the data and critically revised the manuscript.
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