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Sixty four sickle cell anemia subjects had LDH values greater than the 75th percentile and 62 had values less than the 25th percentile (Figure 2A, Table 1).
Two hundred sixty three sickle cell anemia subjects identified by sequencing the HBB locus, with or without coincident α thalassemia, were included [14].
Eleven postmalarial subjects (mean age 28.1 months, SD 6.2) and 16 nonmalarial anemia subjects (mean age 28.7 months, SD 6.7) had sufficient residual plasma to assay hepcidin on days 1 and/or 15 (n = 48).
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The paternal aunt with a twenty-year history of aplastic anemia (Subject A-IV-25) and also heterozygous for the mutation developed dyspnea and cough at the age of forty-six after our first report.
Another study evaluating the impact of treating anemia in subjects with preserved ejection fraction (HFPEF, Anemia in Heart Failure With a Preserved Ejection Fraction study) on functional capacity, ventricular structure and function, along with overall functional status is under way.
To evaluate the safety and efficacy of epoetin alfa administered in extended-dosing intervals to a target hemoglobin (Hb) level not exceeding 12.0 g/dL for the treatment of anemia in subjects with chronic kidney disease (CKD) not on dialysis.
Thus, iron deficiency based on laboratory studies could not account for the higher proportion of anemia in subjects with low D25 levels.
Odds ratio for anemia in subjects with 25-hydroxyvitamin D deficiency using logistic regressions and controlling for age, gender, and chronic kidney disease was 1.9 (95% CI 1.3 2.7).
A multivariate logistic regression analysis controlling for gender, age, renal insufficiency, and ESA use revealed an OR of 1.9 for anemia in subjects with D25 deficiency versus those with normal D25.
To determine variables independently associated with the development of moderate to severe anemia in subjects hospitalized with CAP, we conducted multivariable logistic regression using backward stepwise variable selection with p < 0.05 for model retention.
(13% of the whole group studied), six with COPD, three with pulmonary embolism and one with important anemia, these subjects showed normal chest X rays and sonographic 'dry lungs'; one patient had the diagnosis changed from COPD to hearth failure.
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