Before aiming to intensify the development procedure of guidelines, the costs and savings of such a strategy need to be investigated thoroughly and executed when the proceeds of the intervention outweighs the costs of it [ 29, 30].
The results suggest that bias decreases the further the interim analysis is in terms of sample size from the final analysis (i.e. as the correlation between stages decreases) and when the chance of proceeding to the final stage of the trial is higher, as is the case for effective arms.
This suggests that unprocessed DNA damage accumulates in sae2 mutants, and when the resection cannot proceed, MRX remains stably associated to the site of damage, and Xrs2 subunit stimulates Tel1 activation, which in turn recruits Rad9 and initiates the downstream checkpoint kinase cascade [ 40, 90, 91] (Table 1).
But as other industries face similar evolutions — what will book design look like if and when the transition to e-books proceeds apace?
A gamelan orchestra accompanies the whole proceeding, and when the gamelan stopped playing, the battle was over," Freedman writes.
The medium was changed the following day, and when the cells reached confluence, we proceeded with the adipocyte differentiation protocol.
Do we ask no questions when the proceeds of corruption come into our own financial system?
Work on the Villa America was proceeding slowly, and when the Murphys went down to Antibes for the summer of 1924 they had to put up again at the Hôtel du Cap.
Be sure to include all fees that apply to the sale, what is to be done with merchandise that does not sell, and when and how the proceeds from the sale will be given to the consignor.
In his orchestral music, these problems of notation were not so difficult, because the instructions on how and when to proceed are given by the conductor.
