In contrast to what was noted in the pre-surfactant era, when BPD was characterized by airway inflammation, fibrosis, and smooth muscle hypertrophy, the "new BPD" is associated with delayed alveolar and vascular development, resulting in simplification of alveolar structures, dysmorphic capillary configurations, and variable extents of interstitial cellularity and fibroproliferation [ 8, 9].
The sequences can be subdivided into five types on the basis of principal lithofacies, and exhibit variable magnitude of facies shift corresponding to variable extents of marine transgression and regression on the shelf.
Instructions to eat more vegetables and fruit to stabilise weight resulted in variable extents of weight reduction including substantial weight loss.
Destructive loss of limbal stem cells or dysfunction of their stromal environment renders many corneas with a clinical entity called limbal stem cell deficiency, which is characterized by variable extents of conjunctival ingrowth depending on the severity of limbal damage.
This tumor is histologically characterized by small gland-forming tumor cells with variable extents of fibrous stroma.
The GABA synthesis, in particular, was affected in 23 IEMs (Fig. 3), with 17 of them exhibiting variable extents of neurological symptoms (Supplementary Material, Table S7).
In B cell lymphomas affecting the cortex, massive infiltration of the meninges and the cortical parenchyma by neoplastic B cells (Fig. 1S) and a variable extent of T cell infiltration and microglia activation were seen.
In contrast, all MS patients showed focal inflammatory demyelinating lesions throughout the central nervous system (CNS) and a variable extent of cortical demyelination and diffuse white matter injury [ 22].
The existence of very different levels of sequence diversity among named species, and the variable extent of gene flow within and between bacterial taxa [ 5], complicates species concepts and definitions.
The productivity of a waterbody varies greatly depending on geographical region, physical characteristics, fisheries biology, and the variable extent of water in any given year, while, the number of fishing households dependent these resources have no fixed relationship with area or production.
Therefore, we used a large multicentre (i.e., heterogeneous) cohort of patients treated with RP and a variable extent of PLND to develop the novel NSS.
